Cairo, Egypt (CNN) -- Egyptian security forces turned water cannons and tear gas on protesters in the early hours of Wednesday morning to try to break up unprecedented anti-government demonstrations, the Interior Ministry said Wednesday.
The government "will not allow any provocative movement or a protest or rallies or demonstrations," the ministry said.
The clampdown comes after thousands of protesters spilled into the streets of Egypt on Tuesday, an unprecedented display of anti-government rage inspired in part by the tumult in the nearby North African nation of Tunisia.
Three people died in the clashes, the country's official news agency said Tuesday -- two protesters and one police officer.
On Wednesday, the interior ministry said 85 officers were injured, some of whom died. The ministry did not say how many had died.
Protest organizers on Facebook called for "strikes and marches in populous neighborhoods" Wednesday, but did not outline specific plans.
"Tomorrow has to be spontaneous and must be in the more populous neighborhoods and not set for any particular time," the post said.
"Entering Tahrir Square will be dangerous and the response of security forces will be overwhelming," the post said, referring to the location of the largest protest Tuesday.
The Interior Ministry put the size of the demonstration in Cairo's Tahrir Square at 10,000 at its peak, falling to 5,000. CNN estimated that demonstration peaked at 15,000 to 20,000.
The ministry urged "citizens to renounce attempts to bid and trade their problems and not lose sight of the consequences of provocation for those who attempt to try to open the door to a state of chaos or portray the situation in the country this way."
Twitter was blocked in Egypt Tuesday, the microblogging site said, adding: "We believe that the open exchange of info & views benefits societies & helps govts better connect w/ their people."
Protesters used social media including Twitter and Facebook to organize the demonstrations and to communicate during the day.
Organizers said they hope to capture the regional momentum for political change set by Tunisians, who forced the collapse of Zine El Abidine Ben Ali's 23-year rule.
Protesters had been expressing their anger over the rising cost of living, failed economic policies and corruption, but all those concerns were distilled into one overriding demand: the resignation of President Hosni Mubarak, in power for three decades.
The outpouring included young and old, Christians and Muslims, students, workers and businesspeople.
"We breathe corruption in the air," said one demonstrator, who along with others said their children have no future.
There were other demonstrations in Cairo suburbs of Heliopolis, Shubra Al-Khaima, Muhandasin and Dar Al-Salam.